Valoración de la calidad del sueño en pacientes con artritis reumatoide, espondiloartritis y lupus eritematoso sistémico: estudio del noreste argentino
Palabras clave:
calidad del sueño, artritis reumatoide, espondilitis anquilosante, lupus eritematoso sistémico
Resumen
Introducción: las patologías autoinmunes y sus tratamientos pueden relacionarse con la calidad del sueño. Objetivos: evaluar la calidad del sueño en pacientes con artritis reumatoide (AR), espondiloartritis (SpA) y lupus eritematoso sistémico (LES) a través del cuestionario de Pittsburgh de calidad del sueño (PSQI) en las provincias del noreste argentino. Materiales y métodos: estudio multicéntrico (filial ARNEA), transversal, analítico y descriptivo. Se incluyeron pacientes con AR, SpA y LES. Se evaluó la calidad del sueño mediante PSQI. Se registraron índices de actividad, cronicidad y tratamientos para cada patología. Se realizó un análisis descriptivo y multivariado. Resultados: se evaluaron 163 pacientes. Predominó la AR, seguida del LES. Según el PSQI, la calidad del sueño fue mala en un 77,3% y el 65% refirió múltiples problemas del sueño. En los pacientes con AR se observó una asociación estadísticamente significativa entre mayor DAS28 y mala calidad del sueño (OR 3.06; IC 95% 1,37-6,84; p=0,006). El uso de corticoides se asoció con un mayor PSQI. No hubo diferencias en la calidad del sueño ni el PSQI según patologías. Conclusiones: la mala calidad del sueño fue altamente prevalente en pacientes con patologías autoinmunes, especialmente en aquellos con mayor actividad inflamatoria. Es importante incorporar la evaluación del sueño en la práctica clínica habitual.Citas
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XI. Costa, DD, Bernatsky S, Dritsa M, et al. Determinants of sleep quality in women with systemic lupus erythematosus. Arthritis Care and Research: Official Journal of the American College of Rheumatology. 2005;53(2):272-278.
XII. Krajewska-Włodarczyk M, Owczarczyk-Saczonek A, Placek W. Sleep disorders in patients with psoriatic arthritis and psoriasis. Rheumatology. 2018;56(5):301-306.
XIII. Chandrasekhara, PKS, Jayachandran NV, Rajasekhar L, et al. The prevalence and associations of sleep disturbances in patients with systemic lupus erythematosus. Modern rheumatology. 2019;19(4):407-415.
XIV. Kasitanon N, Achsavalertsak U, Maneeton B, et al. Associated factors and psychotherapy on sleep disturbances in systemic lupus erythematosus. Lupus. 2013; 22(13):1353-1360.
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XVI. Hughes M, Chalk A, Sharma P, et al. A cross-sectional study of sleep and depression in a rheumatoid arthritis population. Clinical rheumatology. 2021;40(4):1299-1305.
XVII. Detert J, Dziurla R, Hoff P, et al. Effects of treatment with etanercept versus methotrexate on sleep quality, fatigue and selected immune parameters in patients with active rheumatoid arthritis. Clin Exp Rheumatol. 2016;34(5):848-856.
XVIII. Garbarino S, Lanteri P, Bragazzi NL, et al. Role of sleep deprivation in immune-related disease risk and outcomes. Commun Biol. 2021;4(1):1304.
XIX. Fabbri M, Beracci A, Martoni M, et al. Measuring subjective sleep quality: a review. Int J Environ Res Public Health. 2021;18(3):1082.
XX. Zitser J, Allen IE, Falgàs N, et al. Pittsburgh Sleep Quality Index (PSQI) responses are modulated by total sleep time and wake after sleep onset in healthy older adults. PLoS One. 2022 Jun 24;17(6):e0270095.
XXI. Debta DK, Padarabinda Tripathy K, Jain T, et al. Prevalence of sleep disturbances in rheumatoid arthritis and its association with disease severity. A hospital-based cross-sectional observation. Cureus. 2025;17(5):e84767.
XXII. McBeth J, Dixon WG, Moore S, et al. Sleep disturbance and quality of life in rheumatoid arthritis: prospective mHealth Study. J Med Internet Res. 2022; 22;24(4):325-258.
Publicado
2025-06-02
Cómo citar
1.
Ringer A, Antoniol MN, Aste N, Benavente EPI, Gallino J, Schmid MM, Mauri ME, Seewald A, Paris Úrsula V, Bravo M, Catay ER, Sattler ME, Góngora V, Finucci Curi P, Velozo EJ. Valoración de la calidad del sueño en pacientes con artritis reumatoide, espondiloartritis y lupus eritematoso sistémico: estudio del noreste argentino. Rev. Argent. Reumatol. [Internet]. 2 de junio de 2025 [citado 7 de octubre de 2025];36(2). Disponible en: https://ojs.reumatologia.org.ar/index.php/revistaSAR/article/view/957
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Artículo Original
