Comparison between seronegative rheumatoid arthritis and polyarticular psoriatic arthritis: cross-sectional study in a Brazilian cohort

  • Annelise Perachi Costodio Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
  • Letícia Mariussi Legramanti Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
  • Ana Paula Beckhauser Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
  • Barbara S. Kahlow Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
  • Renato Nisihara Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
  • Thelma Skare Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
Keywords: rheumatoid arthritis, psoriatic arthritis, quality of life, depression, cardiovascular risk

Abstract

Objectives: the study compared seronegative RA and polyarticular psoriatic arthritis (APs) in terms of cardiovascular risk, quality of life, depression, and functionality. Materials and methods: data from 45 patients with seronegative RA and 36 with polyarticular APs were analyzed. Questionnaires were used to assess depression (CES-D), functionality (Health Assessment Questionnaire-HAQ), and quality of life (SF-12). Carotid intima-media thickness (cIMT) was measured to assess cardiovascular risk. Results: the results showed similar rates of hypertension, diabetes, and dyslipidemia between both groups. However, patients with APs had higher BMI and abdominal circumference. cIMT was equivalent between groups. Depression and quality of life did not show significant differences. Patients with RA presented worse functionality, according to the HAQ. Conclusions: in our cohort, patients with RA and seronegative APs had similarities in quality of life, depression, and cardiovascular risk, except for differences in BMI and abdominal circumference, which were higher in APs. Functionality was worse in AR compared to APs.

Author Biographies

Annelise Perachi Costodio, Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
Mackenzie Evangelical School of Medicine Paraná
Letícia Mariussi Legramanti, Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
Mackenzie Evangelical School of Medicine Paraná
Ana Paula Beckhauser, Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
Mackenzie Evangelical School of Medicine Paraná
Barbara S. Kahlow, Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
Mackenzie Evangelical School of Medicine Paraná
Renato Nisihara, Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
Mackenzie Evangelical School of Medicine Paraná
Thelma Skare, Mackenzie Evangelical School of Medicine Paraná, Curitiba, Brazil
Mackenzie Evangelical School of Medicine Paraná

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Published
2024-06-11
How to Cite
1.
Costodio AP, Legramanti LM, Beckhauser AP, Kahlow BS, Nisihara R, Skare T. Comparison between seronegative rheumatoid arthritis and polyarticular psoriatic arthritis: cross-sectional study in a Brazilian cohort. Rev. Argent. Reumatol. [Internet]. 2024Jun.11 [cited 2025Jan.15];35(2):38 -44. Available from: https://ojs.reumatologia.org.ar/index.php/revistaSAR/article/view/812
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Original Article