Lymphoma and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome): case report
Keywords:
eosinophilic granulomatosis with polyangiitis, ANCA vasculitis, lymphoma
Abstract
Diverse etiologies can trigger ANCA (antineutrophil cytoplasmic antibodies) vasculitis. These include hematological neoplasms, such as non-Hodgkin lymphomas, which can be associated with different autoantibodies and rheumatological manifestations. These secondary causes are essential to suspect if the disease has a chronic course with a poor response to treatment. In this article, we report an unusual association between eosinophilic granulomatosis with polyangiitis and low-grade non-Hodgkin lymphoma.References
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XII. Stemmler HJ, Hoelzl M, Moosmann N, Becker C, Lennertz A, Babaryka G. Lymphadenopathy and constitutional symptoms. Progress of a low-grade follicular lymphoma? Internist (Berl) 2006 May;47(5):528-32
XIII. Vougiouklakis T, Mitselou A, Agnantis NJ. Churg-Strauss syndrome (allergic granulomatous angiitis) associated with T lymphoblastic lymphoma. In Vivo 2004 Jul-Aug;18(4):477-9.
XIV. Calonje JE, Greaves MW. Cutaneous extravascular necrotizing granuloma (Churg-Strauss) as a paraneoplastic manifestation of non-Hodgkin's B-cell lymphoma. J R Soc Med 1993 Sep;86(9):549-50.
XV. Finan MC, Winkelmann RK. Cutaneous extravascular necrotizing granuloma and lymphocytic lymphoma. Arch Dermatol 1983 May;119(5):419-22.
XVI. Le Roy A, Terrier B, London J, Paugam A, Mouthon L, Lifermann F. Angioimmunoblastic T-cell lymphoma mimicking eosinophilic granulomatosis with polyangiitis (Churg-Strauss). Joint Bone Spine 2019 Mar;86(2):273-274.
XVII. Kawauchi M, Watanabe T, Hattori T, Suzuki A, Ishizu A, Jodo S. Eosinophilic granulomatosis with polyangiitis mimicking peripheral T-cell lymphoma, not otherwise specified. Scand J Rheumatol 2019 Mar;48(2):171-172.
XVIII. Byrne N, Murphy A, O'Dwyer M. Cutaneous hypereosinophilia secondary to a low-grade B-cell lymphoma. Int J Dermatol 2019 Aug;58(8):e146-e147.
XIX. Wang L, Zhang G, Zheng W, Tian X, Li M, Zeng X, Zhang F. Intra-abdominal mass, obstructive jaundice, and eosinophilia. Rheumatol Immunol Res 2022 Jul 6;3(2):90-92.
XX. Navarro-Román L, Medeiros LJ, Kingma DW, Zarate-Osrno A, Nguyen V, Samoszuk M, Jaffe ES. Malignant lymphomas of B-cell lineage with marked tissue eosinophilia. A report of five cases. Am J Surg Pathol 1994;18:347.
II. Baldini C, Talarico R, Della Rossa A, Bombardieri S. Clinical manifestations and treatment of Churg-Strauss syndrome. Rheum Dis Clin N Am 2010;36:527-543.
III. Naschitz JE, Rosner I, Rozenbaum M, Elias N, Yeshurun D. Cancer-associated rheumatic disorders. Semin Arthritis Rheum1995;24:231-41.
IV. Mody GM, Cassim B. Rheumatologic manifestations of malignancy. Curr Opin Rheumatol 1997;9:75-9.
V. Fain O, Hamidou M, Cacoub P, Godeau B, Wechsler B, ParièsJ, et al. Vasculitides associated with malignancies: analysis of sixty patients. Arthritis Rheum 2007 Dec 15;57(8):1473-80.
VI. Wang X, Peng Y, Gao J, Han S, Li Y. Risk of malignancy in Behçet disease: a meta-analysis with systematic review. Medicine (Baltimore) 2019 Nov;98(44):e17735.
VII. Kurzrock R, Cohen PR. Vasculitis and cancer. Clin Dermatol 1993;11:175-87.
VIII. Fain O, Guillevin L, Kaplan G, Sicard D, Lemaire V, Godeau P, et al. Vasculitis and neoplasms: 14 cases. Ann Med Interne (Paris) 1991;142:486-504.
IX. Blanco R, Martínez-Taboada VM, Rodríguez-Valverde V, García-Fuentes M. Cutaneous vasculitis in children and adults: associated diseases and etiologic factors in 303 patients. Medicine (Baltimore) 1998;77:403-18.
X. Varoczy L, Lajos G, Margit Z, Gyula S, Arpad I. Malignant lymphoma-associated autoimmune disease-a descriptive epidemiological study. Rheumatol Int. 2002;22:233-7.
XI. Shang W, Ning Y, Xu X, Li M, Guo S, Han M, et al. Incidence of cancer in ANCA-associated vasculitis: a meta-analysis of observational studies. PLoS One 2015 May 14;10(5):e0126016.
XII. Stemmler HJ, Hoelzl M, Moosmann N, Becker C, Lennertz A, Babaryka G. Lymphadenopathy and constitutional symptoms. Progress of a low-grade follicular lymphoma? Internist (Berl) 2006 May;47(5):528-32
XIII. Vougiouklakis T, Mitselou A, Agnantis NJ. Churg-Strauss syndrome (allergic granulomatous angiitis) associated with T lymphoblastic lymphoma. In Vivo 2004 Jul-Aug;18(4):477-9.
XIV. Calonje JE, Greaves MW. Cutaneous extravascular necrotizing granuloma (Churg-Strauss) as a paraneoplastic manifestation of non-Hodgkin's B-cell lymphoma. J R Soc Med 1993 Sep;86(9):549-50.
XV. Finan MC, Winkelmann RK. Cutaneous extravascular necrotizing granuloma and lymphocytic lymphoma. Arch Dermatol 1983 May;119(5):419-22.
XVI. Le Roy A, Terrier B, London J, Paugam A, Mouthon L, Lifermann F. Angioimmunoblastic T-cell lymphoma mimicking eosinophilic granulomatosis with polyangiitis (Churg-Strauss). Joint Bone Spine 2019 Mar;86(2):273-274.
XVII. Kawauchi M, Watanabe T, Hattori T, Suzuki A, Ishizu A, Jodo S. Eosinophilic granulomatosis with polyangiitis mimicking peripheral T-cell lymphoma, not otherwise specified. Scand J Rheumatol 2019 Mar;48(2):171-172.
XVIII. Byrne N, Murphy A, O'Dwyer M. Cutaneous hypereosinophilia secondary to a low-grade B-cell lymphoma. Int J Dermatol 2019 Aug;58(8):e146-e147.
XIX. Wang L, Zhang G, Zheng W, Tian X, Li M, Zeng X, Zhang F. Intra-abdominal mass, obstructive jaundice, and eosinophilia. Rheumatol Immunol Res 2022 Jul 6;3(2):90-92.
XX. Navarro-Román L, Medeiros LJ, Kingma DW, Zarate-Osrno A, Nguyen V, Samoszuk M, Jaffe ES. Malignant lymphomas of B-cell lineage with marked tissue eosinophilia. A report of five cases. Am J Surg Pathol 1994;18:347.
Published
2023-12-30
How to Cite
1.
Gandino IJ, Muñoz SA, Fescina MM, Cayetti AL, Lutgen S, Basta MC. Lymphoma and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome): case report. Rev. Argent. Reumatol. [Internet]. 2023Dec.30 [cited 2025Jan.15];34(4):135 -138. Available from: https://ojs.reumatologia.org.ar/index.php/revistaSAR/article/view/790
Section
Clinical Case
Copyright (c) 2023 on behalf of the authors. Reproduction rights: Argentine Society of Rheumatology
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