Consensus of vaccine recommendations in adults with autoimmune chronic in ammatory rheumatic diseases

Abstract

Chronic autoimmune inflammatory rheumatic diseases (ERCD) are a set of pathologies characterized by joint and systemic involvement, which frequently cause pain, functional disability and deterioration in quality of life. These include: rheumatoid arthritis, systemic lupus erythematosus, scleroderma, inflammatory myopathy, spondyloarthritis, vasculitis, among others. Most rheumatic diseases have an important autoinflammatory component, with marked deregulation of various aspects of the immune system. One of these is autoimmunity, which can be defined as the appearance of a humoral and/or cellular immune response against self-proteins (autoantigens) located in various tissues. Autoimmune diseases are currently considered to be multifactorial disorders that show considerable complexity and heterogeneity despite having a common pathogenesis: loss of self-tolerance.