Adherence to treatment in patients with rheumatoid arthritis
Abstract
Objective: this study aims to evaluate the compliance of pharmacological treatment in patients with RA and identify the factors that may affect it. Materials and methods: observational, analytical and cross-sectional study. Surveys were conducted on 176 randomly selected patients from a private center specialized in Rheumatology located in the southern suburbs of the province of Buenos Aires (CER Medical Institute - Quilmes), between September 2015 and July 2016, by telephone by trained non-medical volunteers of the Articular Foundation. The BAM, CQR19 questionnaires were used and the patient’s perception of their degree of adherence to the treatment was investigated, dividing it into two groups: total compliance or partial/no compliance. Sociodemographic data, disease status, treatment, comorbidities and habits were collected.References
I. Aletaha Daniel, Neogi Tuhina, Silman Alan J, Funovits Julia, Bingham Clifton O, Birnbaum Neal S, Burmester Gerd R, Bykerk Vivian P, Cohen Marc D, et al. 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/ European League Against Rheumatism collaborative initiative. Arthritis & Rheumatology September 2010;62(9):2569-2581.
II. Smolen Josef S, Breedveld Ferdinand C, Burmester Gerd R, Bykerk Vivian, Dougados Maxime, Emery Paul, et al. Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis. 2016 Jan;75(1):3-15.
III. Hughes D, Cowell W, Koncz T, Cramer J; International Society for Pharmacoeconomics & Outcomes Research Economics of Medication Compliance Working Group. Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations. Value Health. 2007 Nov-Dec;10(6):498-509.
IV. Horne R, et al Concordance, adherence and compliance in medicine taking. Report for the National Coordinating Centre for NHS Service Delivery and Organisation. (2005).
V. Drosos AA, et al. Methotrexate therapy in rheumatoid arthritis. A two year prospective follow-up. Clin Rheumatol 1990;9:333-41.
VI. Papadopoulos et al. Disease modifying antirheumatic drugs in early rheumatoid arthritis: a long term observational study. J Rheumatol 2002;29:261-6.
VII. Tuncay R, et al Factors affecting drug treatment compliance in patients with rheumatoid arthritis. Rheumatol Int. 2007;27:743-746.
VIII. Brus H, et al. Determinants of compliance with medication in patients with rheumatoid arthritis: the importance of self-efficacy expectations. Patient Educ Couns 1999;36:57-64.
IX. Grant W. et al. Merging Veterans Affairs Rheumatoid Arthritis Registry and Pharmacy Data to Assess Methotrexate Adherence and Disease Activity in Clinical Practice Arthritis Care & Research December 2011; 63(12):1680-1690.
X. Di Matteo MR. Enhancing patient adherence to medical recommendations. JAMA 1994;271:79, 83.
XI. Komninos ID, Micheli K , Roumeliotaki T, Horne R Adaptation and validation of the Beliefs about Medicines Questionnaire (BMQ) in primary care patients in Greece. European Journal for Person Centered Healthcare Vol 1 Issue 1 pp 224-231.
XII. Citera G, Arriola MS, Maldonado-Cocco JA, Rosemffet MG, Sánchez MM, Goñi MA, Spindler A, Lucero E, Berman A. Validation and crosscultural adaptation of an argentine spanish version of the health assessment questionnaire disability index. J Clin Rheumatol. 2004 Jun;10(3):110-5.
XIII. van den Bemt BJF, van Lankveld GJMW. How can we improve adherence to therapy by patients with rheumatoid arthritis? Nat Clin Pract Rheumatol 2007;3:681.
XIV. Chaparro del Moral R, Rillo O, Benegas M, Correa M, Citera G, Maldonado Cocco J, Casado G, Caputo V, Helling C, Tamborenea MN, Mysler E, Tate G, Takashima L, Secco A, Salcedo M, Baños A, Cowan P, Molina J, Cavillon E, Exeni I, Gobbi C, Scublinsky D. Rev Arg Reumatol. 2013;24(4):18-26.
XV. A dherencia al tratamiento de pacientes con artritis reumatoidea que reciben medicamentos biológicos. Rev Arg Reumatol. 2013;24(4):18-26.
XVI. Waimann CA, Marengo MF, de Achaval S, Cox VL, Garcia-Gonzalez A, Reveille JD, Richardson MN, Suarez Almazor ME. Electronic Monitoring of Oral Therapies in Ethnically Diverse and Economically Disadvantaged Patients with Rheumatoid Arthritis. Consequences of Low Adherence. Arthritis Rheum 2013 Jun;65(6):1421-1429.
XVII. H arrold LR, Andrade SE. Medication adherence of patients with selected rheumatic conditions: a systematic review of the literature. Semin Arthritis Rheum 2009;38:396-402.
XVIII. M arengo MF, Suarez-Almazor ME. Improving treatment adherence in patients with rheumatoid arthritis: what are the options? Int J Clin Rheumatol. 2015 October 1; 10(5):345-356.
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