Development of psoriasis during treatment with Abatacept in rheumatoid arthritis

  • J.A. Riera JB Iturraspe Hospital, Santa Fe, Argentina
  • J.A. Riera JB Iturraspe Hospital, Santa Fe, Argentina
  • J.L. Musuruana JB Iturraspe Hospital, Santa Fe, Argentina
  • C.A. Costa JB Iturraspe Hospital, Santa Fe, Argentina
  • J.A. Cavallasca JB Iturraspe Hospital, Santa Fe, Argentina
DOI: https://doi.org/10.47196/rar.v30i2.458
Keywords: psoriasis, Abatacept, arthritis

Abstract

Abatacept is the first biological agent approved for the treatment of Rheumatoid Arthritis (RA) that acts blocking interaction of T lymphocytes. Although its efficacy in psoriasis and psoriatic arthritis has been reported, there are reports of drug induced psoriasis as well as reactivation of cutaneous lesions. A woman with a history of RA under treatment with Abatacept IV presented erythematous-scaly and pruritic macules on the entire body surface, clinically and histologically compatible with psoriasis. The suspension of treatment with Abatacept caused the disappearance of the cutaneous lesions. More than 4 years later he is in treatment with Rituximab without presenting cutaneous lesions.

Author Biographies

J.A. Riera, JB Iturraspe Hospital, Santa Fe, Argentina
Rheumatology and Systemic Autoimmune Diseases Section
J.A. Riera, JB Iturraspe Hospital, Santa Fe, Argentina
Rheumatology and Systemic Autoimmune Diseases Section
J.L. Musuruana, JB Iturraspe Hospital, Santa Fe, Argentina
Rheumatology and Systemic Autoimmune Diseases Section
C.A. Costa, JB Iturraspe Hospital, Santa Fe, Argentina
Rheumatology and Systemic Autoimmune Diseases Section
J.A. Cavallasca, JB Iturraspe Hospital, Santa Fe, Argentina
Rheumatology and Systemic Autoimmune Diseases Section

References

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Published
2019-06-01
How to Cite
1.
Riera J, Riera J, Musuruana J, Costa C, Cavallasca J. Development of psoriasis during treatment with Abatacept in rheumatoid arthritis. Rev. Argent. Reumatol. [Internet]. 2019Jun.1 [cited 2024Oct.18];30(2):33 -5. Available from: https://ojs.reumatologia.org.ar/index.php/revistaSAR/article/view/458
Issue
Vol. 30 No. 2 (2019): April-June 2019
Section
Clinical Case

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