Asociación entre la variación de glóbulos blancos y las manifestaciones clínicas, anticuerpos e infecciones en adultos con lupus eritematoso sistémico

Belén María Virasoro; Cecilia Pisoni

doi:10.47196/rar.v33i3.668

Belén María Virasoro Sección Reumatología, CEMIC. Buenos Aires, Argentina
Cecilia Pisoni Sección Reumatología, CEMIC. Buenos Aires, Argentina

DOI: https://doi.org/10.47196/rar.v33i3.668

Palabras clave: leucopenia, linfopenia, neutropenia, glóbulos blancos, lupus eritematoso sistémico

Resumen

Introducción: la asociación de leucopenia, linfopenia y neutropenia con la presencia de autoanticuerpos, manifestaciones clínicas e infecciones en pacientes con lupus eritematoso sistémico (LES) no está bien establecida. Los objetivos de este estudio fueron analizar los cambios en los recuentos de leucocitos y linfocitos en pacientes con LES y su asociación con manifestaciones clínicas, autoanticuerpos y riesgo de infecciones. Materiales y métodos: se recolectaron retrospectivamente los valores de leucocitos, linfocitos y neutrófilos. Se agruparon a los pacientes en cinco categorías: recuento de glóbulos blancos normales, leucopenia (persistente o intermitente) y linfopenia (persistente o intermitente). Se registraron las manifestaciones clínicas, los autoanticuerpos acumulados, el daño, la mortalidad, las infecciones y los tratamientos inmunosupresores recibidos de cada paciente.

Biografía del autor/a

Belén María Virasoro, Sección Reumatología, CEMIC. Buenos Aires, Argentina

Sección Reumatología, Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno” (CEMIC), Ciudad Autónoma de Buenos Aires, Argentina

Cecilia Pisoni, Sección Reumatología, CEMIC. Buenos Aires, Argentina

Sección Reumatología, Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno” (CEMIC), Ciudad Autónoma de Buenos Aires, Argentina

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