Evolución y factores pronósticos en pacientes lúpicos con admisión en unidad de terapia intensiva
Palabras clave:
Lupus Eritematoso Sistémico, factores pronósticos, Unidad de Terapia Intensiva
Resumen
El objetivo de este estudio fue evaluar las causas de ingreso y la mortalidad de pacientes con LES admitidos en Unidad de Terapia Intensiva (UTI), e identificar factores de riesgo asociados con mortalidad así como la utilidad de la escala de APACHE II como factor de pronóstico. Se estudiaron retrospectivamente pacientes con diagnóstico de LES acorde al ACR 1997, ingresados en UTI del Hospital Córdoba desde junio de 2008 a marzo del 2011. Se analizaron datos demográficos, características de la enfermedad, causas de admisión, escala de APACHE II en las primeras 24 hs de internación, tratamiento realizado, días de internación y mortalidad. Valores de p <0,05 fueron considerados estadísticamente significativos.Citas
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XIII. Moreels M, Melot Ch, Leeman M. Prognosis of patients with systemic rheumatic diseases admitted to the intensive care unit. Intensive Care Med 2005; 31:591-593.
XIV. Ñamendys-Silva SA, et al. Prognostic factors in patients with systemic lupus erythematosus admitted to the intensive care unit. Lupus 2009; 18, 1252-1258.
XV. S Rinaldi et al. Health-related quality of life in Italian patients with systemic lupus erythematosus I. Relationship between physical and mental dimension and impact of age. Rheumat 2004; 12:1574-1579.
XVI. Siripaitoon B, Lertwises S, Uea-Areewongsa P, Khwannimit B. A study of Thai patients with systemic lupus erythematosus in the medical intensive care unit: epidemiology and predictors of mortality. Lupus 2015 Jan; 24 (1):98-106.
XVII. Zimlichman E, Rothschild J, Shoenfeld Y, Zandman-Goddard G. Good prognosis for hospitalized SLE patients with non-related disease. Autoimmun Rev. 2014 Nov; 13(11):1090-3.
XVIII. Han BK, Bhatia R, Traisak P, Hunter K, Milcarek B, Schorr C, Eid H, Feinstein D, Cronin P, Kolasinski SL. Clinical presentations and outcomes of systemic lupus erythematosus patients with infection admitted to the intensive care unit. Lupus 2013 Jun; 22(7):690-6.
II. Jacobson DL, Gange SJ, Rose NR, Graham NMH. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin Immunol Immunopathol 1997; 84:223-243.
III. KM, Michet CJJ, Thumboo J, Sunku J, O0Fallon WM, Gabriel SE. Trends in the incidence and mortality of systemic lupus erythematosus 1950-1992. Arthritis Rheum 1999; 42:46-50.
IV. Petri M. Epidemiology of systemic lupus erythematosus. Best Pract Res Clin Rheumatol 2002;16:847-858.
V. Raj R, Murin S, Matthay RA, Wiedemann HP. Systemic lupus erythematosus in the intensive care unit. Crit Care Clin 2002; 18:781-803.
VI. Godeau B, Mortier E, Roy P, et al. Short and long-term outcomes for patients with systemic rheumatic diseases admitted to intensive care units: a prognostic study of 181 patients. J Reumatol 1997; 24:1317-1323
VII. Fessler BJ. Infectious diseases in systemic lupus erythematosus: risk factors, management and prophylaxis. Best Pract Res Clin Rheumatol 2002; 16:281-291.
VIII. Zonana Nacach A, Barr SG, Magder LS, Petri M. Damage in systemic lupus erythematosus and its association with corticosteroids. Arthritis Rheum 2000; 43:1801-1808.
IX. Ansell SM, Bedhesi S, Ruff B, et al. Study of critically ill patients with systemic lupus erythematosus. Crit Care Med 1996; 24:981-984.
X. Duffy KN, Duffy CM, Gladman DD. Infection and disease activity in systemic lupus erythematosus: a review of hospitalized patients. J Rheumatol 1991; 18:1180-1184.
XI. Zonana-Nacach A, Camargo-Coronel A, Yañez P, Sanchez L, Jimenez-Balderas FJ, Fraga A. Infections in outpatients with systemic lupus erythematosus: a prospective study. Lupus 2001; 10:505-510.
XII. Hsu CL, Chen KY, Yeh PS, et al. Outcome and prognostic factors in critically ill patients with systemic lupus erythematosus: a retrospective study. Crit Care 2005; 9:R177-R183.
XIII. Moreels M, Melot Ch, Leeman M. Prognosis of patients with systemic rheumatic diseases admitted to the intensive care unit. Intensive Care Med 2005; 31:591-593.
XIV. Ñamendys-Silva SA, et al. Prognostic factors in patients with systemic lupus erythematosus admitted to the intensive care unit. Lupus 2009; 18, 1252-1258.
XV. S Rinaldi et al. Health-related quality of life in Italian patients with systemic lupus erythematosus I. Relationship between physical and mental dimension and impact of age. Rheumat 2004; 12:1574-1579.
XVI. Siripaitoon B, Lertwises S, Uea-Areewongsa P, Khwannimit B. A study of Thai patients with systemic lupus erythematosus in the medical intensive care unit: epidemiology and predictors of mortality. Lupus 2015 Jan; 24 (1):98-106.
XVII. Zimlichman E, Rothschild J, Shoenfeld Y, Zandman-Goddard G. Good prognosis for hospitalized SLE patients with non-related disease. Autoimmun Rev. 2014 Nov; 13(11):1090-3.
XVIII. Han BK, Bhatia R, Traisak P, Hunter K, Milcarek B, Schorr C, Eid H, Feinstein D, Cronin P, Kolasinski SL. Clinical presentations and outcomes of systemic lupus erythematosus patients with infection admitted to the intensive care unit. Lupus 2013 Jun; 22(7):690-6.
Publicado
2015-03-01
Cómo citar
1.
Hancevic M, Gobbi C, Alba P, Babini A, Albiero E. Evolución y factores pronósticos en pacientes lúpicos con admisión en unidad de terapia intensiva. Rev. Argent. Reumatol. [Internet]. 1 de marzo de 2015 [citado 25 de abril de 2024];26(1):23 -28. Disponible en: https://ojs.reumatologia.org.ar/index.php/revistaSAR/article/view/625
Sección
Artículo Original
Derechos de autor 2015 A nombre de los autores. Derechos de reproducción: Sociedad Argentina de Reumatología
Esta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-SinObrasDerivadas 4.0.
